Friday, March 18, 2016

The Emotional Brain and Lack of Sleep

Lack of sleep can affect several systems in the body. There is a lot of evidence on it’s effect on immune regulation, metabolic control, and neurocognitive processes such as learning and memory. However, evidence is lacking on it’s role in regulating the emotional brain state. There is clinical evidence to suggest the sleep and emotion interact, especially since nearly all psychiatric and neurological disorders express sleep disruption in some way. Aside from sleep, there is a lot of knowledge on how emotion is regulated. The amygdala has a huge role in processing emotional information and the medial-prefrontal cortex (MPFC) is thought to exhibit an inhibitory, top-down control of the amygdala which results in appropriate emotional responses.

Using a sleep-deprivation group and a control group, this experiment ran several scan on the participants while performing an emotional stimulus viewing test. The test used stimuli that ranged along a gradient from emotionally neutral to more aversive images. The recorded observation show that the amygdala expressed significant activation to the increasingly negative stimuli, however the sleep-deprived group exhibited a +60% greater magnitude of activation. Similar reactions were seen in both groups in response to the neutral stimuli, but a huge difference in activation could be seen increasing amounts dependent on the strength of the stimuli. This led to implications that there can be definite relationships between sleep disturbances and mood disorders.

My interest from this article came from the work I do with the Health Educational Awareness Team (HEAT) on campus. My favorite workshop to teach is Sleep and Relaxation because there is a lot of relevant and really interesting information presented that most people don’t typically learn about. There is this one section that we present on that is specifically geared towards sleep and its effect on the emotional brain. A 60 Minutes segment is shown in order to solidify the information, and the information provided matches almost exactly with what this article presented. The role and activation of the amygdala in response to certain stimuli is largely uncontrolled in sleep-deprived individuals. This can often be why people are cranky, or younger children throw tantrums when they are exhausted. However, I find this particularly interesting due to its effects on mental health; especially for the college aged population. There’s this large push or thought process that sleep may not be that important, but I think if we are able to show people that it may really help control or slow the onset of depression, anxiety or other disorders, more people will pay attention to its benefits.  


1 comment:

  1. I find it quite interesting that despite most college age students having access to information that proves the importance of sleep and the positive impact it can have on all areas of ones life, many college students still devalue it and don't see it as something that is necessary and rather as something that can be sacrificed. I believe this is a cause for pondering upon and evaluation the emphasis our culture puts on particular things over others. For example, students are expected to push themselves to achieve more and more- from academics to extracurricular activities that set them apart, all the while maintaining a job to provide for themselves. When a social life also is placed in this ring, it is easy to see how sleep loses its priority. Maybe a cultural shift is necessary so that we can apply our neurological and psychological learnings to positively shift our values and societal behavior for the overall betterment and increase in quality of life.

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